H Hanabusa Selected Research

MC710

1/2017	A phase III clinical trial of a mixture agent of plasma-derived factor VIIa and factor X (MC710) in haemophilia patients with inhibitors.
11/2013	A Phase II clinical trial of a mixture of plasma-derived factor VIIa and factor X (MC710) in haemophilia patients with inhibitors: haemostatic efficacy, safety and pharmacokinetics/pharmacodynamics.
3/2013	Results of clot waveform analysis and thrombin generation test for a plasma-derived factor VIIa and X mixture (MC710) in haemophilia patients with inhibitors--phase I trial: 2nd report.
1/2012	Clinical pharmacological study of a plasma-derived factor VIIa and factor X mixture (MC710) in haemophilia patients with inhibitors--phase I trial.

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H Hanabusa Research Topics

Disease

9	Hemophilia A (Haemophilia) 01/2017 - 07/2000
5	Hemorrhage 01/2017 - 06/2001
3	Disseminated Intravascular Coagulation 01/2017 - 01/2012
2	Hemophilia B (Haemophilia B) 07/2016 - 01/2016
1	Pain (Aches) 01/2017
1	Pancytopenia 05/2001
1	Infections 07/2000
1	Coinfection 03/2000

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2012
4	MC710IBA 01/2017 - 01/2012
4	Factor VIIa (Activated Factor VII)IBA 01/2017 - 01/2012
3	Dacarbazine (DIC)FDA LinkGeneric 01/2017 - 01/2012
3	Factor X (Stuart Factor)IBA 01/2017 - 01/2012
2	Factor IX (Coagulation Factor IX)FDA LinkGeneric 07/2016 - 01/2016
2	nonacog beta pegolIBA 07/2016 - 01/2016
2	factor VIII-Fc fusion proteinIBA 01/2016 - 11/2014
2	Factor VIII (Coagulation Factor VIII)IBA 09/2015 - 11/2014
2	recombinant FVIIa (rFVIIa)FDA Link 03/2013 - 06/2001
1	PotassiumIBA 01/2017
1	von Willebrand FactorIBA 11/2014
1	Thrombin FDA Link 03/2013
1	anti-inhibitor coagulant complexIBA 03/2013
1	Hemostatics (Antihemorrhagics)IBA 06/2001
1	PercollIBA 07/2000
1	DNA (Deoxyribonucleic Acid)IBA 07/2000
1	RNA (Ribonucleic Acid)IBA 07/2000
1	Transforming Growth Factor beta (TGF-beta)IBA 03/2000
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 03/2000

Therapy/Procedure

1	Intravenous Infusions 11/2014
1	Injections 06/2001
1	Splenectomy 05/2001